TabletWise.com
 

Mantle Cell Lymphoma

An aggressive, usually diffuse non-Hodgkin lymphoma composed of small to medium sized B-lymphocytes (centrocytes). Most patients present with advanced stage disease with lymphadenopathy, hepatosplenomegaly, and bone marrow involvement. The gastrointestinal tract is the most commonly affected extranodal site by this type of non-Hodgkin lymphoma. The vast majority of cases express the t(11;14)(q13;q32) resulting in the rearrangement of the BCL-1 gene and the overexpression of cyclin D1 mRNA.

Symptoms of Mantle Cell Lymphoma

The following features are indicative of Mantle Cell Lymphoma:
  • swollen lymph nodes
  • fever
  • night sweats
  • weight loss
  • fatigue
  • gastrointestinal obstruction
  • multiple intestinal polyps
  • high white blood cell count
  • anorexia
It is possible that Mantle Cell Lymphoma shows no physical symptoms and still is present in a patient.

Get TabletWise Pro

Thousands of Classes to Help You Become a Better You.

Common Causes of Mantle Cell Lymphoma

The following are the most common causes of Mantle Cell Lymphoma:
  • somatic DNA damage

Risk Factors for Mantle Cell Lymphoma

The following factors may increase the likelihood of Mantle Cell Lymphoma:
  • older age
  • being male
  • White race
  • autoimmune conditions
  • being on immune suppressing medications
  • HIV/AIDS
  • HTLV-1
  • Epstein-Barr virus
  • helicobacter pylori infection

Prevention of Mantle Cell Lymphoma

Yes, it may be possible to prevent Mantle Cell Lymphoma. Prevention may be possible by doing the following:
  • maintain a healthy immune system
  • maintain a healthy weight
  • eat a healthy diet

Occurrence of Mantle Cell Lymphoma

Number of Cases

The following are the number of Mantle Cell Lymphoma cases seen each year worldwide:
  • Very rare between 1K - 10K cases

Common Age Group

Mantle Cell Lymphoma most commonly occurs in the following age group:
  • Aged > 50 years

Common Gender

Mantle Cell Lymphoma can occur in any gender.

Lab Tests and Procedures for Diagnosis of Mantle Cell Lymphoma

The following lab tests and procedures are used to detect Mantle Cell Lymphoma:
  • Physical exam: To diagnose for mantle cell lymphoma
  • Flow cytometry test: To diagnose for mantle cell lymphoma
  • Bone marrow aspiration: To diagnose for mantle cell lymphoma
  • Biopsy: To diagnose for mantle cell lymphoma

Doctor for Diagnosis of Mantle Cell Lymphoma

Patients should visit the following specialists if they have symptoms of Mantle Cell Lymphoma:
  • Hematologist
  • Oncologist

Complications of Mantle Cell Lymphoma if untreated

Yes, Mantle Cell Lymphoma causes complications if it is not treated. Below is the list of complications and problems that may arise if Mantle Cell Lymphoma is left untreated:
  • bone marrow
  • bone and neurologic lesions

Procedures for Treatment of Mantle Cell Lymphoma

The following procedures are used to treat Mantle Cell Lymphoma:
  • Chemotherapy: Helps to kill cancerous cells
  • Immunotherapy: Helps in treating the condition
  • Hematopoietic stem cell transplantation: Helps in treating the condition

Self-care for Mantle Cell Lymphoma

The following self-care actions or lifestyle changes may help in the treatment or management of Mantle Cell Lymphoma:
  • Exercise: To reduce or prevent lymphoma
  • Quit smoking: Avoid the use of tobacco

Alternative Medicine for Treatment of Mantle Cell Lymphoma

The following alternate medicine and therapies are known to help in the treatment or management of Mantle Cell Lymphoma:
  • Massage therapy: Relax muscles and alleviate body pain
  • Meditation: To ease the side effects of medicines
  • Relaxation exercises: Helps reducing stress

Patient Support for Treatment of Mantle Cell Lymphoma

The following actions may help Mantle Cell Lymphoma patients:
  • Join online support groups: Provides support to patients and their families living with Mantle cell lymphoma

Last updated date

This page was last updated on 2/04/2019.
This page provides information for Mantle Cell Lymphoma.

Sign Up



Share

Share with friends, get 20% off
Invite your friends to TabletWise learning marketplace. For each purchase they make, you get 20% off (upto $10) on your next purchase.